David R. Spigel : rechercher sur Z-Library

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Articles (146)
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1

Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057)

Horn, Leora, Spigel, David R., Vokes, Everett E., Holgado, Esther, Ready, Neal, Steins, Martin, Poddubskaya, Elena, Borghaei, Hossein, Felip, Enriqueta, Paz-Ares, Luis, Pluzanski, Adam, Reckamp, Karen

Journal:

Journal of Clinical Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 970 KB

english, 2017

2

Weekly docetaxel versus docetaxel/gemcitabine in the treatment of elderly or poor performance status patients with advanced nonsmall cell lung cancer : A randomized phase 3 trial of the Minnie Pearl Cancer Research Network

John D. Hainsworth, David R. Spigel, Cindy Farley, Dianna L. Shipley, James D. Bearden, Jitendra Gandhi, Gerry Ann Houston, F. Anthony Greco

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 145 KB

english, 2007

3

Bevacizumab and everolimus in the treatment of patients with metastatic melanoma : A phase 2 trial of the Sarah Cannon Oncology Research Consortium

John D. Hainsworth, Jeffrey R. Infante, David R. Spigel, James D. Peyton, Dana S. Thompson, Cassie M. Lane, Bobby L. Clark, Mark S. Rubin, David F. Trent, Howard A. Burris III

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 197 KB

english, 2010

4

Phase II Trial of Mapatumumab, a Fully Human Agonist Monoclonal Antibody to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor 1 (TRAIL-R1), in Combination With Paclitaxel and Carboplatin in Patients With Advanced Non–Small-Cell Lung Cancer

von Pawel, Joachim, Harvey, Jimmie H., Spigel, David R., Dediu, Mircea, Reck, Martin, Cebotaru, Cristina L., Humphreys, Robin C., Gribbin, Matthew J., Fox, Norma Lynn, Camidge, D. Ross

Journal:

Clinical Lung Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 569 KB

english, 2014

5

Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

Borghaei, Hossein, Paz-Ares, Luis, Horn, Leora, Spigel, David R., Steins, Martin, Ready, Neal E., Chow, Laura Q., Vokes, Everett E., Felip, Enriqueta, Holgado, Esther, Barlesi, Fabrice, Kohlhäufl, Mar

Journal:

New England Journal of Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 303 KB

english, 2015

6

PS01.59: CheckMate 370: A Master Protocol of Phase 1/2 Studies of Nivolumab as Maintenance or First-Line ± Standard-of-Care Therapies in Advanced NSCLC

Blumenschein, George, Chandler, Jason, Garon, Edward B., Waterhouse, David, Goldman, Jonathan W., Gunuganti, Vijay K., Boccia, Ralph, Spigel, David, Glaspy, John, Berry, Donald A., Korytowsky, Beata,

Journal:

Journal of Thoracic Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 206 KB

english, 2016

7

Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohort

Burris, Howard A, Bakewell, Suzanne, Bendell, Johanna C, Infante, Jeffrey, Jones, Suzanne F, Spigel, David R, Weiss, Glen J, Ramanathan, Ramesh K, Ogden, Angela, Von Hoff, Daniel

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2017

8

Evaluation of health-related quality of life and symptoms in patients with advanced non-squamous non-small cell lung cancer treated with nivolumab or docetaxel in CheckMate 057

Reck, Martin, Brahmer, Julie, Bennett, Bryan, Taylor, Fiona, Penrod, John R., DeRosa, Michael, Dastani, Homa, Spigel, David R., Gralla, Richard J.

Journal:

European Journal of Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 736 KB

english, 2018

9

Avelumab versus docetaxel in patients with platinum-treated advanced non-small-cell lung cancer (JAVELIN Lung 200): an open-label, randomised, phase 3 study

Barlesi, Fabrice, Vansteenkiste, Johan, Spigel, David, Ishii, Hidenobu, Garassino, Marina, de Marinis, Filippo, Özgüroğlu, Mustafa, Szczesna, Aleksandra, Polychronis, Andreas, Uslu, Ruchan, Krzakowski

Journal:

The Lancet Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 345 KB

english, 2018

10

Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non–Small-Cell Lung Cancer: Results From the CA209-003 Study

Gettinger, Scott, Horn, Leora, Jackman, David, Spigel, David, Antonia, Scott, Hellmann, Matthew, Powderly, John, Heist, Rebecca, Sequist, Lecia V., Smith, David C., Leming, Philip, Geese, William J.,

Journal:

Journal of Clinical Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 788 KB

english, 2018

11

Combination chemotherapy with gemcitabine and irinotecan in patients with previously treated carcinoma of an unknown primary site : A Minnie Pearl Cancer Research Network Phase II trial

John D. Hainsworth, David R. Spigel, Eric L. Raefsky, Michel E. Kuzur, Kathleen Yost, Michael Kommor, Sharlene Litchy, F. Anthony Greco

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 88 KB

english, 2005

12

Combination therapy with fludarabine and rituximab followed by alemtuzumab in the first-line treatment of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma : A phase 2 trial of the Minnie Pearl Cancer Research Network

John D. Hainsworth, Elizabeth R. Vazquez, David R. Spigel, Eric Raefsky, James D. Bearden, Ruben A. Saez, F. Anthony Greco

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 106 KB

english, 2008

13

Final survival and safety results from a multicenter, open-label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer

David R. Spigel, Ming Lin, Vincent O'Neill, John D. Hainsworth

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 162 KB

english, 2008

14

Weekly treatment with bortezomib for patients with recurrent or refractory multiple myeloma : A phase 2 trial of the Minnie Pearl Cancer Research Network

John D. Hainsworth, David R. Spigel, John Barton, Cindy Farley, Marshall Schreeder, Jeremy Hon, F. Anthony Greco

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 134 KB

english, 2008

15

Neoadjuvant chemotherapy/gefitinib followed by concurrent chemotherapy/radiation therapy/gefitinib for patients with locally advanced squamous carcinoma of the head and neck

John D. Hainsworth, David R. Spigel, Howard A. Burris III, Tiffanie M. Markus, Dianna Shipley, Michel Kuzur, Scott Lunin, F. Anthony Greco

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 228 KB

english, 2009

16

Oxaliplatin and capecitabine in the treatment of patients with recurrent or refractory carcinoma of unknown primary site : A phase 2 trial of the Sarah Cannon Oncology Research Consortium

John D. Hainsworth, David R. Spigel, Howard A. Burris III, Dianna Shipley, Cindy Farley, Ines M. Macias-Perez, John Barton, F. Anthony Greco

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 156 KB

english, 2010

17

Chemotherapy in metastatic and locally advanced non-small cell lung cancer

David R. Spigel, F. Anthony Greco

Journal:

Seminars in Surgical Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 114 KB

english, 2003

18

A drug interaction study evaluating the pharmacokinetics and toxicity of sorafenib in combination with capecitabine

Jeffrey R. Infante, Suzanne F. Jones, Johanna C. Bendell, F. Anthony Greco, Denise A. Yardley, Cassie M. Lane, David R. Spigel, John D. Hainsworth, Howard A. Burris III

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 219 KB

english, 2012

19

Stratified flow interactions with a suspended canopy

David R. Plew, Robert H. Spigel, Craig L. Stevens, Roger I. Nokes, Mark J. Davidson

Journal:

Environmental Fluid Mechanics

Année:

2006

Langue:

english

Fichier:

PDF, 599 KB

english, 2006

20

HER2 overexpressing metastatic breast cancer

David R. Spigel, Harold J. Burstein

Journal:

Current Treatment Options in Oncology

Année:

2002

Langue:

english

Fichier:

PDF, 399 KB

english, 2002

21

A phase II open-label randomized study to assess the efficacy and safety of selumetinib (AZD6244 [ARRY-142886]) versus capecitabine in patients with advanced or metastatic pancreatic cancer who have failed first-line gemcitabine therapy

György Bodoky, Constanta Timcheva, David Robert Spigel, Phillip Joseph La Stella, Tudor Eliade Ciuleanu, G. Pover, N. C. Tebbutt

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 640 KB

english, 2012

22

Erratum to: A phase II open-label randomized study to assess the efficacy and safety of selumetinib (AZD6244 [ARRY-142886]) versus capecitabine in patients with advanced or metastatic pancreatic cancer who have failed first-line gemcitabine therapy

György Bodoky, Constanta Timcheva, David Robert Spigel, Phillip Joseph La Stella, Tudor Eliade Ciuleanu, G. Pover, N. C. Tebbutt

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 61 KB

english, 2012

23

A Phase II Study of Higher Dose Weekly Topotecan in Relapsed Small-Cell Lung Cancer

David R. Spigel, F. Anthony Greco, Howard A. Burris III, Dianna L. Shipley, Bobby L. Clark, Robert C. Whorf, Edward R. Arrowsmith, John D. Hainsworth

Journal:

Clinical Lung Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 318 KB

english, 2011

24

Preliminary Treatment Patterns and Safety Outcomes for Non—Small-Cell Lung Cancer from ARIES, a Bevacizumab Treatment Observational Cohort Study

David Spigel, Priya Kumar, Siew Leng Teng, Lisa Wang, Willis Navarro, Thomas Lynch

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 79 KB

english, 2008

25

Tracheoesophageal Fistula Development and Concurrent Chemoradiation and Bevacizumab in Non—Small-Cell Lung Cancer

David R. Spigel, F. Anthony Greco, Cindy Farley, Christina Meng, Howard A. Burris III, Denise Yardley, Nancy Peacock, John D. Hainsworth

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 64 KB

english, 2008

26

Neuroendocrine Carcinoma of Unknown Primary Site

David R. Spigel, John D. Hainsworth, F. Anthony Greco

Journal:

Seminars in Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 104 KB

english, 2009

27

A Phase II Randomized Crossover Study of Liposomal Doxorubicin Versus Weekly Docetaxel in the First-line Treatment of Women With Metastatic Breast Cancer

Denise A. Yardley, Howard A. Burris III, David R. Spigel, Bobby L. Clark, Elizabeth Vazquez, Dianna Shipley, John Barton, Dana Thompson, Ignacio Montes, F. Anthony Greco, John D. Hainsworth

Journal:

Clinical Breast Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 359 KB

english, 2009

28

A Phase II Trial of Gemcitabine/Carboplatin with or Without Trastuzumab in the First-Line Treatment of Patients with Metastatic Breast Cancer

Denise A. Yardley, Howard A. Burris III, Lisa Simons, David R. Spigel, F. Anthony Greco, John H. Barton, Dianna Shipley, David Drosick, John D. Hainsworth

Journal:

Clinical Breast Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 117 KB

english, 2008

29

Weekly Gemcitabine and Trastuzumab in the Treatment of Patients With HER2-Overexpressing Metastatic Breast Cancer

Denise A. Yardley, Howard A. Burris III, Sarah Hanson, F. Anthony Greco, David R. Spigel, John Barton, John D. Hainsworth

Journal:

Clinical Breast Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 108 KB

english, 2009

30

Weekly Docetaxel and Bortezomib as First-Line Treatment for Patients with Hormone-Refractory Prostate Cancer: A Minnie Pearl Cancer Research Network Phase II Trial

John D. Hainsworth, Anthony A. Meluch, David R. Spigel, John Barton Jr, Lisa Simons, Christina Meng, Bruce Gould, F. Anthony Greco

Journal:

Clinical Genitourinary Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 147 KB

english, 2007

31

Treatment of Advanced Renal Cell Carcinoma with the Combination Bevacizumab/Erlotinib/Imatinib: A Phase I/II Trial

John D. Hainsworth, David R. Spigel, Jeffrey A. Sosman, Howard A. Burris III, Cindy Farley, Heather Cucullu, Kathleen Yost, Lowell L. Hart, Linda Sylvester, David M. Waterhouse, F. Anthony Greco

Journal:

Clinical Genitourinary Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 120 KB

english, 2007

32

Single-Agent Gefitinib in Patients with Untreated Advanced Non–Small-Cell Lung Cancer and Poor Performance Status: A Minnie Pearl Cancer Research Network Phase II Trial

David R. Spigel, John D. Hainsworth, Emily R. Burkett, Howard A. Burris, Denise A. Yardley, Melodie Thomas, Suzanne F. Jones, Natalie R. Dickson, Daniel C. Scullin, James E. Bradof, James R. Rubinsak,

Journal:

Clinical Lung Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 519 KB

english, 2005

33

Paclitaxel/Carboplatin/Gemcitabine Versus Gemcitabine/Vinorelbine in Advanced Non–Small-Cell Lung Cancer: A Phase II/III Study of the Minnie Pearl Cancer Research Network

F. Anthony Greco, David R. Spigel, Michel E. Kuzur, Dianna Shipley, James R. Gray, Dana S. Thompson, Howard A. Burris, Denise A. Yardley, Asim Pati, Charles D. Webb, Jitendra G. Gandhi, John D. Hainsw

Journal:

Clinical Lung Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 120 KB

english, 2007

34

A Randomized Phase II Trial of Oral Topotecan Versus Docetaxel in the Second-Line Treatment of Non–Small-Cell Lung Cancer

Suzanne Jones, Dana Thompson, John Barton, Jeff Patton, Dianna Shipley, F. Anthony Greco, David Spigel, Jeff Infante, Howard A. Burris III

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 124 KB

english, 2008

35

What Is the Role of Novel Taxanes in Non–Small-Cell Lung Cancer?

David R. Spigel, F. Anthony Greco

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 115 KB

english, 2008

36

“Dominance” in the Laboratory Rat: The Emergence of Grooming

Dr. Irwin M. Spigel, David Fraser

Journal:

Année:

1974

Langue:

english

Fichier:

PDF, 801 KB

english, 1974

37

Phase II Study of Bevacizumab and Chemoradiation in the Preoperative or Adjuvant Treatment of Patients With Stage II/III Rectal Cancer

David R. Spigel, Johanna C. Bendell, Michael McCleod, Dianna L. Shipley, Edward Arrowsmith, E. Kirk Barnes, Jeffrey R. Infante, Howard A. Burris III, F. Anthony Greco, John D. Hainsworth

Journal:

Clinical Colorectal Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 378 KB

english, 2012

38

A phase I, dose-escalation study of pomalidomide (CC-4047) in combination with gemcitabine in metastatic pancreas cancer

Jeffrey R. Infante, Suzanne F. Jones, Johanna C. Bendell, David R. Spigel, Denise A. Yardley, Colin D. Weekes, Wells A. Messersmith, John D. Hainsworth, Howard A. Burris III

Journal:

European Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 368 KB

english, 2011

39

Waldenstrom's macroglobulinemia presenting as new-onset ascites

Elena Martinez Stoffel, David R. Spigel, Norman D. Grace

Journal:

Journal of Hepatology

Année:

2004

Langue:

english

Fichier:

PDF, 45 KB

english, 2004

40

HER2 and surgery: more questions to answer

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 56 KB

english, 2003

41

Phase 1 Results From a Study of Romidepsin in Combination With Gemcitabine in Patients With Advanced Solid Tumors

Jones, Suzanne F., Infante, Jeffrey R., Spigel, David R., Peacock, Nancy W., Thompson, Dana S., Greco, F. Anthony, McCulloch, William, Burris III, Howard A.

Journal:

Cancer Investigation

Année:

2012

Langue:

english

Fichier:

PDF, 197 KB

english, 2012

42

Concurrent chemoradiation followed by esophageal resection vs chemoradiation alone for localized esophageal cancer

John D. Hainsworth, Anthony A. Meluch, James R. Gray, David R. Spigel, Christina Meng, James D. Bearden, Robert Hermann, F. Anthony Greco

Journal:

Community Oncology

Année:

2007

Langue:

english

Fichier:

PDF, 329 KB

english, 2007

43

Treatment Update in Small-Cell Lung Cancer: From Limited to Extensive Disease

Spigel, David R.

Journal:

Current Treatment Options in Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 152 KB

english, 2012

44

Treatment Rationale Study Design for the MetLung Trial: A Randomized, Double-Blind Phase III Study of Onartuzumab (MetMAb) in Combination With Erlotinib Versus Erlotinib Alone in Patients Who Have Received Standard Chemotherapy for Stage IIIB or IV Met-Positive Non–Small-Cell Lung Cancer

David R. Spigel, Martin J. Edelman, Tony Mok, Kenneth O'Byrne, Luis Paz-Ares, Wei Yu, Karen Rittweger, Holger Thurm

Journal:

Clinical Lung Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 255 KB

english, 2012

45

Phase II study of maintenance sunitinib following irinotecan and carboplatin as first-line treatment for patients with extensive-stage small-cell lung cancer

Spigel, David R., Greco, F. Anthony, Rubin, Mark S., Shipley, Dianna, Thompson, Dana S., Lubiner, Eric T., Eakle, Janice F., Quinn, Raven, Burris, Howard A., Hainsworth, John D.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 407 KB

english, 2012

46

Phase II trial of ixabepilone and carboplatin with or without bevacizumab in patients with previously untreated advanced non-small-cell lung cancer

Spigel, David R., Anthony Greco, F., Waterhouse, David M., Shipley, Dianna L., Zubkus, John D., Bury, Martin J., Webb, Charles D., Hart, Lowell L., Gian, Victor G., Infante, Jeffrey R., Burris, Howard

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 231 KB

english, 2012

47

Waldenstrom’s macroglobulinemia presenting as new-onset ascites

Elena Stoffel, David Spigel, Norman Grace

Journal:

American Journal of Gastroenterology

Année:

2002

Langue:

english

Fichier:

PDF, 52 KB

english, 2002

48

Trastuzumab Regimens for HER2-Overexpressing Metastatic Breast Cancer

David R. Spigel, Harold J. Burstein

Journal:

Clinical Breast Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 141 KB

english, 2003

49

Phase II Trial of Weekly Docetaxel, Vinorelbine, and Trastuzumab in the First-Line Treatment of Patients with HER2-Positive Metastatic Breast Cancer

Jeffrey R. Infante, Denise A. Yardley, Howard A. Burris III, F. Anthony Greco, Cindy P. Farley, Charles Webb, David R. Spigel, John D. Hainsworth

Journal:

Clinical Breast Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 120 KB

english, 2009

50

A Phase II Feasibility Trial of Dose-Dense Docetaxel Followed by Doxorubicin/Cyclophosphamide as Adjuvant or Neoadjuvant Treatment for Women with Node-Positive or High-Risk Node-Negative Breast Cancer

Denise A. Yardley, Howard A. Burris III, Cindy P. Farley, John H. Barton, Nancy W. Peacock, David R. Spigel, F. Anthony Greco, John D. Hainsworth

Journal:

Clinical Breast Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 109 KB

english, 2008